Tournament was held on 11/20/2021.
| 1st | Katie Barker | Triad High School |
| 2nd | Grace Sletten | Fenwick High School |
| 3rd | Laiba Baloch | College Preparatory School of America |
| 4th | Rithik Thekiniath | Illinois Mathematics and Science Academy |
| 5th | Alyssa Ryan | Illinois Mathematics and Science Academy |
| 1st | Dhruv Patel | Illinois Mathematics and Science Academy |
| 2nd | Henry DeVivo | University High School |
| 3rd | Alexander Boehne | Triad High School |
| 4th | Nandana Varma | Illinois Mathematics and Science Academy |
| 5th | Salma Mohammedi | College Preparatory School of America |
| 1st | Yajath Narra & Daniel Zhang | University High School |
| 2nd | Sachit Muduli & Mitchell Hayes | University High School |
| 3rd | Vidyoot Senthilvenkatesh & Aruuke Ulanbek | Illinois Mathematics and Science Academy |
| 4th | Colin Crisp & Melody Behzadi | British International School Chicago South Loop |
| 5th | Ethan Ehrenhofer & Julia Podgorski | Grant Community High School |
| 1st | Oliver Ni & Andy Tang | Illinois Mathematics and Science Academy |
| 2nd | Irene Liu & Miles Massey | Illinois Mathematics and Science Academy |
| 3rd | Gabe Floyd & Henry Shang | University High School |
| 4th | Joseph Shim & Harris Dorgan | University High School |
| 5th | Sumedha Surubhotla & Aashima Sisodia | Illinois Mathematics and Science Academy |